Define Immunoglobulin D
► Molecular weight of IgD is185, 000 Daltons and has a sedimentation coefficient of 7S. ► Its concentration in serum is about 3 mg/100ml, which constitutes about 0.2% of total Ig. ► It is mostly intra vascular in distribution. ► Its half-life is about 3days. ► It is rich in carbohydrates. ► IgD along with IgM occurs on the surface of unstimulated or mature B cells and serves as a reorganization receptor for antigens. ► No biological effect or function has been identified for IgD.
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