Briefly Describe Immunoglobulin (Ig) A.


  • 12 Mar, 2012

    1) It is the second most abundant class containing 10-13% if serum immunoglobulins.2) It has a half-life of 6-8 days.3) IgA is actively secreted by mucosal associated lymphoidal tissue (MALT).4) Its molecular weight is 60,000 Daltons.5) IgA is synthesized locally by plasma cells and dimerized intra-cellular before secretion, with the help of cysteine rich polypeptide, called the J chain, which has a molecular weight of 15,000.IgA functions by inhibiting the adherence of coated microorganisms to the surface of mucosal cells.

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